Why Plan Before You Start?
Rigorous study planning reduces bias, increases transparency, and strengthens the credibility of your findings. Pre-registering a protocol ensures your methods are documented before results are known — protecting against selective reporting and HARKing (hypothesizing after results are known). BioClaritas provides structured tools to plan every aspect of your study before data collection begins.
DAG Evaluation for Study Design
Directed acyclic graphs (DAGs) are the standard tool for formalizing causal assumptions in epidemiology and clinical research. By mapping out the relationships between your exposure, outcome, confounders, and mediators, you can determine the correct adjustment strategy and identify potential sources of bias before starting your study. BioClaritas helps you build, evaluate, and publish your DAG as part of your protocol.
Supported Protocol Types
BioClaritas supports protocol preparation for systematic reviews and meta-analyses, randomized controlled trials, cohort studies, case-control studies, observational studies, scoping reviews, diagnostic accuracy studies, and more. Each protocol type includes structured templates with fields relevant to your study design.
From Protocol to Publication
Your protocol is not just a planning tool — it becomes a citable, pre-registered document when published on BioClaritas Preprints. After completing your study, your final manuscript links back to the protocol, demonstrating adherence to your pre-registered plan. This workflow supports the highest standards of transparent, reproducible research.